Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385738 | 0.75 | TAAR1 (0.51) | KDM1AALDH1A1CASP3SENP8SENP7 | |
| SCHEMBL28867385 | 0.75 | TAAR1 (0.51) | KDM1AALDH1A1CASP3SENP8SENP7 | |
| SCHEMBL7747310 | 0.71 | TAAR1 (0.34) | ALDH1A1MAPTHPGDNPSR1KDM4E | |
| SCHEMBL19554795 | 0.71 | KDM1A (0.46) | KDM1ASLC6A4SLC6A2SLC6A3MTNR1A | |
| SCHEMBL28703337 | 0.71 | KDM1A (0.46) | KDM1ASLC6A4SLC6A2SLC6A3MTNR1A | |
| SCHEMBL20385796 | 0.70 | TAAR1 (0.46) | KDM1ASLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL4723659 | 0.70 | KDM1A (0.45) | KDM1ASLC6A4SLC6A2SLC6A3MTNR1A | |
| SCHEMBL20385693 | 0.70 | TAAR1 (0.46) | KDM1ASLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL3610201 | 0.70 | TAAR1 (0.62) | — | |
| SCHEMBL3610206 | 0.70 | TAAR1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555100-B1 | BENZODIAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENT | AGENEBIO INC (US) | 2023-05-10 | — | — | EP | disclosed |