Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.48 |
| ▸ | BRDT | Q58F21 | 8/20 | 0.46 |
| ▸ | DNER | Q8NFT8 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2544179 | 1.00 | BRD4 (0.48) | BRD4BRDTDNERADORA3TSPO | |
| SCHEMBL2544227 | 0.86 | BRD4 (0.49) | BRD4BRDTDNERADORA3TSPO | |
| SCHEMBL2544229 | 0.86 | BRD4 (0.49) | BRD4BRDTDNERADORA3TSPO | |
| SCHEMBL2540394 | 0.86 | BRD4 (0.53) | BRD4BRDTDNERADORA3TSPO | |
| SCHEMBL2538161 | 0.86 | BRD4 (0.51) | BRD4BRDTDNER | |
| SCHEMBL2538155 | 0.86 | BRD4 (0.51) | BRD4BRDTDNER | |
| SCHEMBL3215768 | 0.85 | BRD4 (0.69) | BRD4BRDTDNERADORA3TSPO | |
| SCHEMBL2535981 | 0.83 | BRD4 (0.51) | BRD4BRDTDNERADORA3TSPO | |
| SCHEMBL2535984 | 0.83 | BRD4 (0.51) | BRD4BRDTDNERADORA3TSPO | |
| SCHEMBL23320673 | 0.82 | BRD4 (0.56) | BRD4BRDTDNERADORA3TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044042-B2 | Thienotriazolodiazepine compound and medicinal use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-10-25 | — | — | US | disclosed |