Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 14/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.43 |
| ▸ | TTK | P33981 | 5/20 | 0.42 |
| ▸ | LCK | P06239 | 5/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30183124 | 0.93 | PTK6 (0.46) | PTK6AURKBTTKLCK | |
| SCHEMBL22123977 | 0.92 | PTK6 (0.44) | PTK6AURKBTTKPTK2 | |
| SCHEMBL30171824 | 0.92 | PTK6 (0.44) | PTK6AURKBTTKPTK2 | |
| Hydrochloric Acid SCHEMBL30171690 | 0.91 | PTK6 (0.43) | PTK6AURKBTTKPTK2 | |
| SCHEMBL22122922 | 0.91 | PTK6 (0.43) | PTK6AURKBTTK | |
| SCHEMBL30171553 | 0.91 | PTK6 (0.43) | PTK6AURKBTTK | |
| SCHEMBL25444479 | 0.90 | PTK6 (0.42) | PTK6AURKBTTKPTK2 | |
| SCHEMBL22123396 | 0.90 | PTK6 (0.40) | PTK6AURKBTTKLCKPTK2 | |
| SCHEMBL24870811 | 0.90 | PTK6 (0.40) | PTK6AURKBTTKLCKPTK2 | |
| SCHEMBL30171918 | 0.90 | PTK6 (0.40) | PTK6AURKBTTKLCKPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | claimed |