Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 13/20 | 0.46 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22124823 | 0.91 | TTK (0.44) | TTKMAPKAPK5CDK2CDK1PTK6 | |
| SCHEMBL30171592 | 0.91 | TTK (0.44) | TTKMAPKAPK5CDK2CDK1PTK6 | |
| SCHEMBL22124726 | 0.81 | TTK (0.48) | TTKMAPKAPK5PTK6BRAF | |
| SCHEMBL25013088 | 0.81 | TTK (0.51) | TTKMAPKAPK5PTK6 | |
| SCHEMBL22160152 | 0.81 | MAPKAPK5 (0.46) | TTKMAPKAPK5CDK2PTK6BRAF | |
| Hydrochloric Acid SCHEMBL30171803 | 0.81 | TTK (0.47) | TTKMAPKAPK5PTK6BRAF | |
| SCHEMBL25013701 | 0.80 | TTK (0.50) | TTKMAPKAPK5PTK6 | |
| SCHEMBL22124765 | 0.80 | TTK (0.48) | TTKMAPKAPK5PTK6BRAF | |
| SCHEMBL22124789 | 0.79 | TTK (0.46) | TTKMAPKAPK5PTK6BRAF | |
| SCHEMBL22124907 | 0.79 | TTK (0.46) | TTKMAPKAPK5PTK6BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898630-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-05-10 | — | — | EP | disclosed |