Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 13/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.41 |
| ▸ | LCK | P06239 | 5/20 | 0.41 |
| ▸ | TTK | P33981 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24910529 | 0.94 | PTK6 (0.46) | PTK6AURKBLCK | |
| SCHEMBL25170317 | 0.92 | PTK6 (0.46) | PTK6AURKBLCKTTKMAPKAPK5 | |
| SCHEMBL22139158 | 0.92 | PTK6 (0.46) | PTK6AURKBLCKTTKMAPKAPK5 | |
| SCHEMBL22123983 | 0.91 | PTK6 (0.42) | PTK6AURKBLCKTTKDRD2 | |
| SCHEMBL30178012 | 0.91 | PTK6 (0.44) | PTK6AURKBLCKTTKMAPKAPK5 | |
| SCHEMBL22124899 | 0.90 | PTK6 (0.56) | PTK6AURKBLCKTTK | |
| SCHEMBL30177799 | 0.90 | PTK6 (0.56) | PTK6AURKBLCKTTK | |
| Hydrochloric Acid SCHEMBL25173591 | 0.89 | PTK6 (0.55) | PTK6AURKBLCKTTK | |
| SCHEMBL24910536 | 0.89 | PTK6 (0.42) | PTK6AURKBLCKTTK | |
| SCHEMBL22124078 | 0.89 | PTK6 (0.43) | PTK6AURKBLCKTTKMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898630-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-05-10 | — | — | EP | disclosed |