Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 11/20 | 0.44 |
| ▸ | TTK | P33981 | 3/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | JAK1 | P23458 | 3/20 | 0.38 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24910956 | 0.88 | PTK6 (0.45) | PTK6TTKLCKAURKBJAK2 | |
| SCHEMBL30171568 | 0.86 | PTK6 (0.48) | PTK6TTKLCKAURKBMAPKAPK5 | |
| SCHEMBL22125188 | 0.86 | PTK6 (0.48) | PTK6TTKLCKAURKBMAPKAPK5 | |
| SCHEMBL22123966 | 0.86 | PTK6 (0.49) | PTK6TTKLCKAURKBMAPKAPK5 | |
| SCHEMBL22124133 | 0.85 | PTK6 (0.48) | PTK6TTKLCKAURKB | |
| Hydrochloric Acid SCHEMBL30171611 | 0.85 | PTK6 (0.48) | PTK6TTKLCKAURKBMAPKAPK5 | |
| SCHEMBL22124228 | 0.84 | MAPKAPK5 (0.49) | PTK6TTKLCKAURKBMAPKAPK5 | |
| SCHEMBL30177634 | 0.84 | MAPKAPK5 (0.49) | PTK6TTKLCKAURKBMAPKAPK5 | |
| SCHEMBL25013649 | 0.83 | PTK6 (0.45) | PTK6TTKLCKAURKBMAPKAPK5 | |
| SCHEMBL22124582 | 0.83 | PTK6 (0.47) | PTK6TTKLCKAURKBMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898630-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-05-10 | — | — | EP | disclosed |