Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 20/20 | 0.80 |
| ▸ | BRPF1 | P55201 | 20/20 | 0.80 |
| ▸ | TAF1 | P21675 | 19/20 | 0.80 |
| ▸ | BRD4 | O60885 | 3/20 | 0.75 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.69 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.69 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.69 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404506 | 0.89 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404593 | 0.89 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL23318441 | 0.87 | BRD1 (0.72) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19405037 | 0.86 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404501 | 0.85 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404467 | 0.85 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19405032 | 0.85 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404458 | 0.84 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404614 | 0.84 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404464 | 0.82 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145782-A1 | p53 MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230145782-A1 | p53 MODULATORS AND USES THEREOF | TP53, TP53BP1, MDM2 | BRD1 1579/4885BRPF1 469/4885TAF1 1077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.