SCHEMBL25446352

SCHEMBL25446352

OC1(O)Oc2ccc(Br)cc2O1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.50
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
BLM P54132 1/20 0.41
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
CA1 P00915 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
ALOX15 P16050 2/20 0.34
HTR2C P28335 1/20 0.34
AKR1B1 P15121 1/20 0.33
CA12 O43570 1/20 0.32
PDK2 Q15119 1/20 0.31
CYP2A6 P11509 2/20 0.30
CES2 O00748 1/20 0.30
GALR3 O60755 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31085202 0.77 AHR (0.50) AHRLMNAMAPTHTTBLM
SCHEMBL6601303 0.77 AHR (0.50) AHRLMNAMAPTHTTBLM
SCHEMBL361525 0.77 TSHR (0.56) AHRLMNAMAPTHTTBLM
SCHEMBL12046 0.77 AHR (0.50) AHRLMNAMAPTHTTBLM
SCHEMBL316417 0.77 AHR (0.50) AHRLMNAMAPTHTTBLM
SCHEMBL7881729 0.73 MAPT (0.55) LMNAMAPTCA2CA9CA1
SCHEMBL31085080 0.72 MAPT (0.55) AHRLMNAMAPTHTTBLM
SCHEMBL6485133 0.71 AHR (0.48) AHRLMNAMAPTHTTBLM
SCHEMBL12483177 0.71 AHR (0.43) AHRLMNAMAPTHTTBLM
SCHEMBL31085029 0.71 AHR (0.43) AHRLMNAMAPTHTTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023081899-A1 ISOTOPICALLY ENRICHED N-METHYL-1,3-BENZODIOXOLYLBUTANAMINE (MBDB) AND STEREOISOMERS THEREOF TERRAN BIOSCIENCES, INC. (US) 2023-05-11 WO disclosed
WO-2023081895-A1 ISOTOPICALLY ENRICHED ANALOGS OF 5,6-METHYLENEDIOXY-2-AMINOINDANE (MDAI) TERRAN BIOSCIENCES, INC. (US) 2023-05-11 WO disclosed
WO-2023081897-A1 ISOTOPICALLY ENRICHED 3,4-METHYLENEDIOXY-N-ETHYLAMPHETAMINE (MDE) AND STEREOISOMERS THEREOF TERRAN BIOSCIENCES, INC. (US) 2023-05-11 WO disclosed