SCHEMBL25446896

SCHEMBL25446896

O=C1C=CC(=O)N1CN1C(=O)c2ccc(Cc3ccc4c(c3)C(=O)N(CN3C(=O)C=CC3=O)C4=O)cc2C1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 5/20 0.42
FAAH O00519 3/20 0.42
ENPP2 Q13822 1/20 0.38
KDM4E B2RXH2 2/20 0.38
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
MEN1 O00255 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25748808 0.81 CA1 (0.36) MGLLFAAHCA12CA1CA2
SCHEMBL25446898 0.79 CHRM2 (0.50) MEN1KMT2ACA12CA1CA2
SCHEMBL15305649 0.78 TDP1 (0.58) KDM4EMEN1HPGDKMT2APOLB
SCHEMBL18412473 0.78 KDM4E (0.37) MGLLFAAHENPP2KDM4EMEN1
SCHEMBL17735854 0.77 KDM4E (0.49) ENPP2KDM4EHDAC3HDAC4HDAC1
SCHEMBL26832358 0.75 POLB (0.56) ENPP2KDM4EMEN1KMT2ACA12
SCHEMBL26832356 0.75 POLB (0.56) ENPP2KDM4EMEN1KMT2ACA12
SCHEMBL26832339 0.75 POLB (0.56) ENPP2KDM4EMEN1KMT2ACA12
SCHEMBL17735857 0.74 KDM4E (0.69) ENPP2KDM4EMEN1KMT2ACA1
SCHEMBL13819251 0.73 CA1 (0.35) KDM4ECA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230147906-A1 CHOPPED CARBON FIBER BUNDLE AND METHOD FOR PRODUCING CHOPPED CARBON FIBER BUNDLE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-05-11 US disclosed