Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 8/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.36 |
| ▸ | CDK2 | P24941 | 4/20 | 0.36 |
| ▸ | CCNK | O75909 | 3/20 | 0.36 |
| ▸ | CDK9 | P50750 | 3/20 | 0.36 |
| ▸ | CCND3 | P30281 | 2/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | BCL6 | P41182 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25449111 | 0.89 | EGFR (0.36) | MAPK3LCKEGFRNPC1 | |
| SCHEMBL24179107 | 0.87 | MEN1 (0.43) | MAPK3LCKEGFRNPC1ALK | |
| SCHEMBL23153915 | 0.85 | LRRK2 (0.35) | MAPK3CCNA2CDK2CCNKCDK9 | |
| SCHEMBL24179306 | 0.84 | MAPK3 (0.44) | MAPK3 | |
| SCHEMBL15600758 | 0.82 | CCNA2 (0.43) | MAPK3CCNA2CDK2CCNKCDK9 | |
| SCHEMBL30833778 | 0.82 | CCNA2 (0.43) | MAPK3CCNA2CDK2CCNKCDK9 | |
| SCHEMBL29761996 | 0.82 | CCNA2 (0.43) | MAPK3CCNA2CDK2CCNKCDK9 | |
| SCHEMBL10042752 | 0.81 | MAPK3 (0.40) | MAPK3LCKCCNA2CDK2CCNK | |
| SCHEMBL10042753 | 0.81 | MAPK3 (0.44) | MAPK3LCKCCNA2CDK2CCNK | |
| SCHEMBL23154046 | 0.77 | MEN1 (0.38) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393930-A1 | CRYSTAL FORMS, PREPARATION METHOD AND APPLICATION OF ARYL PHOSPHINE OXIDE COMPOUND | Chengdu Di'Ao Jiuhong Pharmaceutical Factory (CN) | 2024-07-03 | — | — | EP | disclosed |
| EP-4177258-A1 | ARYLPHOSPHINE OXIDE COMPOUNDS AND USE THEREOF | Chengdu Di'Ao Jiuhong Pharmaceutical Factory (CN) | 2023-05-10 | — | — | EP | disclosed |