Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 6/20 | 0.43 |
| ▸ | CDK2 | P24941 | 6/20 | 0.43 |
| ▸ | CCNK | O75909 | 4/20 | 0.43 |
| ▸ | CDK9 | P50750 | 4/20 | 0.43 |
| ▸ | CCND3 | P30281 | 3/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BCL6 | P41182 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15600758 | 1.00 | CCNA2 (0.43) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL29761996 | 1.00 | CCNA2 (0.43) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL19312831 | 0.87 | CCNA2 (0.45) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL22520101 | 0.87 | LRRK2 (0.38) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL21558104 | 0.86 | BCL6 (0.58) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL21557746 | 0.86 | IGF1R (0.51) | CDK2CDK9LRRK2ALKKMT2A | |
| SCHEMBL30701638 | 0.86 | IGF1R (0.51) | CDK2CDK9LRRK2ALKKMT2A | |
| SCHEMBL25530155 | 0.86 | AURKA (0.47) | CDK2ALKKMT2ABCL6JAK2 | |
| SCHEMBL29399794 | 0.85 | LRRK2 (0.42) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL28295859 | 0.82 | ULK1 (0.47) | CDK2CDK9ULK1JAK2MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |