SCHEMBL25449295

SCHEMBL25449295

c1ccc(-n2c3ccccc3c3cc([Si](c4ccccc4)(c4ccccc4)c4cccc(-c5nc(-n6c7ccccc7c7ccccc76)nc(-n6c7ccccc7c7ccccc76)n5)c4)ccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
PTGER4 P35408 1/20 0.34
KMT2A Q03164 3/20 0.33
IL1R1 P14778 1/20 0.33
ABCG2 Q9UNQ0 3/20 0.32
ALDH1A1 P00352 3/20 0.32
HTT P42858 2/20 0.32
MEN1 O00255 2/20 0.32
MAPT P10636 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
MAPK1 P28482 1/20 0.31
PTPN1 P18031 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CSNK2A1 P68400 1/20 0.31
TSHR P16473 1/20 0.30
ABCB1 P08183 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23622528 0.95 KDM4E (0.40) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL23622426 0.95 KDM4E (0.40) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL23622518 0.95 KDM4E (0.40) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL23622427 0.95 KDM4E (0.40) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL25478516 0.95 KDM4E (0.33) L3MBTL1KDM4EATMKMT2AABCG2
SCHEMBL23622648 0.94 L3MBTL1 (0.42) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL17463272 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL24089262 0.92 KDM4E (0.37) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL26376010 0.92 KDM4E (0.37) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL26376009 0.92 KDM4E (0.37) L3MBTL1KDM4EATMPTGER4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230141905-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-11 US disclosed
US-20230141905-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-11 US disclosed