Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.51 |
| ▸ | PARP11 | Q9NR21 | 8/20 | 0.51 |
| ▸ | PARP1 | P09874 | 8/20 | 0.51 |
| ▸ | CDC7 | O00311 | 2/20 | 0.42 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BUB1 | O43683 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25452107 | 0.84 | PARP10 (0.47) | PARP10PARP11PARP1CDC7DBF4 | |
| SCHEMBL25452551 | 0.74 | BUB1 (0.43) | BUB1ADRA2APKN2 | |
| SCHEMBL7581652 | 0.72 | PARP1 (0.56) | PARP10PARP11PARP1ACHE | |
| SCHEMBL25451943 | 0.71 | KCNH2 (0.42) | PDPK1ADRA2AMAPK13CDK1RPS6KB1 | |
| SCHEMBL7590531 | 0.70 | PARP11 (0.56) | PARP10PARP11PARP1CDC7PDPK1 | |
| SCHEMBL26970286 | 0.70 | SYK (0.51) | CDC7ROCK2PRKACACDK9JAK3 | |
| SCHEMBL25452044 | 0.69 | ADRA2A (0.40) | PDPK1ADRA2AMKNK1CDK1RPS6KB1 | |
| SCHEMBL830807 | 0.68 | PARP1 (1.00) | PARP10PARP11PARP1PDPK1ACHE | |
| SCHEMBL8118685 | 0.68 | PARP1 (0.64) | PARP10PARP11PARP1PDPK1ACHE | |
| SCHEMBL6421827 | 0.68 | PARP1 (0.64) | PARP10PARP11PARP1PDPK1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081800-A1 | ALPHA-2A ADRENERGIC RECEPTOR MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-11 | — | — | WO | disclosed |