Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949768 | 0.82 | GPR84 (0.47) | GPR84MEN1KMT2AKCNH2CYP1A2 | |
| SCHEMBL14877441 | 0.77 | GPR84 (0.44) | GPR84MEN1KMT2AKCNH2CYP1A2 | |
| SCHEMBL13978021 | 0.73 | GPR84 (0.48) | GPR84KCNH2CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL3664007 | 0.73 | GPR84 (0.44) | GPR84MEN1KMT2AKCNH2CYP1A2 | |
| SCHEMBL6463332 | 0.71 | MEN1 (0.39) | GPR84MEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL92739 | 0.69 | KCNH2 (0.46) | GPR84MEN1KMT2AKCNH2CYP3A4 | |
| SCHEMBL3661591 | 0.68 | GPR84 (0.46) | GPR84KCNH2CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL29523323 | 0.67 | KCNH2 (0.50) | GPR84KCNH2CYP3A4ALDH1A1PKM | |
| SCHEMBL7711334 | 0.67 | KCNH2 (0.50) | GPR84KCNH2CYP3A4ALDH1A1PKM | |
| SCHEMBL31054446 | 0.67 | KCNH2 (0.50) | GPR84KCNH2CYP3A4ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542538-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | Kumiai Chemical Industry Co., Ltd. (JP) | 2013-01-09 | — | — | EP | disclosed |
| WO-2012002096-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |