Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | UGCG | Q16739 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | PRF1 | P14222 | 3/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25453057 | 0.85 | DDB1 (0.40) | DDB1CRBNUGCGMEN1KMT2A | |
| SCHEMBL5986824 | 0.83 | MEN1 (0.55) | DDB1CRBNMEN1KMT2A | |
| SCHEMBL26767589 | 0.82 | UGCG (0.34) | UGCGMEN1KMT2ABRD4GABRA1 | |
| SCHEMBL26767592 | 0.80 | ESR1 (0.40) | CRBNUGCGGABRA1GABRG2GABRB3 | |
| SCHEMBL25457841 | 0.79 | MEN1 (0.40) | DDB1CRBNMEN1KMT2ALRRK2 | |
| SCHEMBL21610984 | 0.79 | LRRK2 (0.46) | DDB1CRBNMEN1KMT2ALRRK2 | |
| SCHEMBL15727774 | 0.77 | BRD4 (0.40) | DDB1CRBNUGCGMEN1KMT2A | |
| SCHEMBL26460455 | 0.77 | UGCG (0.38) | DDB1CRBNUGCGMEN1KMT2A | |
| SCHEMBL26768102 | 0.77 | MEN1 (0.43) | UGCGMEN1KMT2ALRRK2PRF1 | |
| SCHEMBL12559535 | 0.76 | MEN1 (0.55) | DDB1CRBNMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024096753-A1 | NEK7 DEGRADERS AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024094819-A1 | NEK7 DEGRADERS AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2024-05-10 | — | — | WO | disclosed |
| WO-2023081845-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |