Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PRF1 | P14222 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25457841 | 0.85 | MEN1 (0.40) | DDB1CRBNMEN1KMT2ALRRK2 | |
| SCHEMBL21610984 | 0.85 | LRRK2 (0.46) | DDB1CRBNMEN1KMT2ALRRK2 | |
| SCHEMBL21738231 | 0.85 | LRRK2 (0.43) | DDB1CRBNMEN1KMT2ALRRK2 | |
| SCHEMBL25453056 | 0.85 | DDB1 (0.37) | DDB1CRBNMEN1KMT2ALRRK2 | |
| SCHEMBL21610992 | 0.82 | MEN1 (0.55) | MEN1KMT2ALRRK2CYP3A4GAA | |
| SCHEMBL15339545 | 0.82 | KMT2A (0.55) | DDB1CRBNMEN1KMT2ALRRK2 | |
| SCHEMBL27308798 | 0.82 | ALDH1A1 (0.39) | DDB1CRBNMEN1KMT2ALRRK2 | |
| SCHEMBL8227244 | 0.80 | MEN1 (0.62) | DDB1CRBNMEN1KMT2A | |
| SCHEMBL26768098 | 0.78 | ALDH1A1 (0.43) | MEN1KMT2ACYP3A4MAPTALDH1A1 | |
| SCHEMBL17193061 | 0.78 | DDB1 (0.39) | DDB1CRBNMEN1KMT2ALRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081845-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |