Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31543992 | 0.84 | BRD4 (0.41) | PARP1DPP4HTR2CHTR2AHTR2B | |
| SCHEMBL29099572 | 0.84 | BRD4 (0.41) | PARP1DPP4HTR2CHTR2AHTR2B | |
| SCHEMBL24649692 | 0.81 | HTR2A (0.43) | PARP1HTR2CHTR2AHTR2BPIK3CG | |
| SCHEMBL25453058 | 0.79 | PARP1 (0.37) | PARP1HTR2CHTR2AHTR2BBRD4 | |
| SCHEMBL25453054 | 0.79 | PARP1 (0.37) | PARP1HTR2CHTR2AHTR2B | |
| SCHEMBL26667753 | 0.75 | PARP1 (0.37) | PARP1LRRK2L3MBTL1BCL2A1 | |
| SCHEMBL14996503 | 0.73 | PARP1 (0.57) | PARP1HTR2CHTR2AHTR2BBRD4 | |
| SCHEMBL31735456 | 0.73 | BRD4 (0.55) | PIK3CGBRD4 | |
| SCHEMBL29209082 | 0.71 | BRD4 (0.42) | PARP1HTR2CHTR2AHTR2BPIK3CG | |
| SCHEMBL26667749 | 0.71 | DPP4 (0.37) | DPP4LRRK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081845-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |