Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24649692 | 0.81 | HTR2A (0.43) | PARP1BRD4MEN1KMT2AALDH1A1 | |
| SCHEMBL25453060 | 0.79 | PARP1 (0.37) | PARP1BRD4MEN1KMT2AHTR2A | |
| SCHEMBL25453054 | 0.79 | PARP1 (0.37) | PARP1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL21608276 | 0.76 | PARP1 (0.39) | PARP1BRD4MEN1KMT2AABCC9 | |
| SCHEMBL29209082 | 0.75 | BRD4 (0.42) | PARP1BRD4MEN1KMT2AHTR2A | |
| SCHEMBL18089021 | 0.73 | PARP1 (0.57) | PARP1BRD4MEN1KMT2AHTR2A | |
| SCHEMBL31239560 | 0.70 | BRD4 (0.41) | PARP1BRD4MEN1KMT2AABCC9 | |
| SCHEMBL29099572 | 0.70 | BRD4 (0.41) | PARP1BRD4MEN1KMT2AHTR2A | |
| SCHEMBL31543992 | 0.70 | BRD4 (0.41) | PARP1BRD4MEN1KMT2AHTR2A | |
| SCHEMBL13892590 | 0.68 | ALDH1A1 (0.37) | BRD4ALDH1A1ALDH2ALDH3A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081845-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |