⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19419598 | 1.00 | — | — | |
| SCHEMBL27117053 | 0.91 | ATM (0.33) | — | |
| SCHEMBL27117028 | 0.91 | ATM (0.33) | — | |
| SCHEMBL20320096 | 0.82 | SLC6A4 (0.34) | — | |
| SCHEMBL18685394 | 0.82 | SLC6A4 (0.34) | — | |
| SCHEMBL21391958 | 0.78 | ATM (0.31) | — | |
| SCHEMBL16625645 | 0.78 | ATM (0.31) | — | |
| SCHEMBL18120030 | 0.78 | ATM (0.31) | — | |
| SCHEMBL23773733 | 0.78 | ATM (0.31) | — | |
| SCHEMBL22752551 | 0.75 | SIGMAR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150975-A1 | COMPOUNDS USED AS KINASE INHIBITORS AND APPLICATION THEREOF | TYK MEDICINES (ZHENGZHOU), INC. (CN) | 2023-05-18 | — | — | US | disclosed |
| US-11648254-B2 | Substituted pyrido[2,3-d]pyrimidines as inhibitors of Ras pathway signaling | KUMQUAT BIOSCIENCES INC. (US) | 2023-05-16 | — | — | US | disclosed |