Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 1.00 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ABAT | P80404 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76433 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL10796330 | 0.97 | LOXL2 (0.94) | LOXL2GFERHRH3ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL3171444 | 0.97 | LOXL2 (0.94) | LOXL2GFERHRH3ALDH1A1CYP3A4 | |
| SCHEMBL3787138 | 0.91 | LOXL2 (0.83) | LOXL2GFERHRH3ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL31716096 | 0.89 | LOXL2 (0.79) | LOXL2GFERHRH3ALDH1A1CYP3A4 | |
| SCHEMBL15828 | 0.86 | HRH3 (0.79) | LOXL2HRH3ABATMAPTTAAR1 | |
| Benzylamine SCHEMBL23044693 | 0.85 | LOXL2 (0.78) | LOXL2CYP3A4TSHRTDP1MAPT | |
| SCHEMBL12634637 | 0.84 | LOXL2 (0.71) | LOXL2GFERALDH1A1CYP3A4TSHR | |
| Sulfuric Acid SCHEMBL2925225 | 0.84 | LOXL2 (0.71) | LOXL2GFERHRH3ALDH1A1CYP3A4 | |
| SCHEMBL10537796 | 0.84 | LOXL2 (0.71) | LOXL2GFERHRH3ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9168316-B2 | Methods for treating obesity | GU YANSONG (US) | 2015-10-27 | — | — | US | claimed |
| US-20140322136-A1 | METHODS FOR TREATING OBESITY | GU YANSONG (US) | 2014-10-30 | — | — | US | claimed |
| US-20110262362-A1 | METHODS FOR TREATING OBESITY | GU YANSONG | 2011-10-27 | — | — | US | claimed |
| WO-2010042868-A2 | METHODS FOR TREATING OBESITY | UNIVERSITY OF WASHINGTON (US) | 2010-04-15 | — | — | WO | claimed |
| US-9168316-B2 | Methods for treating obesity | GU YANSONG (US) | 2015-10-27 | — | — | US | disclosed |
| US-8980852-B2 | Methods for treating obesity | GU YANSONG (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140322136-A1 | METHODS FOR TREATING OBESITY | GU YANSONG (US) | 2014-10-30 | — | — | US | disclosed |
| US-20110262362-A1 | METHODS FOR TREATING OBESITY | GU YANSONG | 2011-10-27 | — | — | US | disclosed |
| WO-2010042868-A2 | METHODS FOR TREATING OBESITY | UNIVERSITY OF WASHINGTON (US) | 2010-04-15 | — | — | WO | disclosed |