Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL25167618 | 0.99 | S1PR1 (0.51) | S1PR1S1PR3S1PR4S1PR5ALOX5 | |
| SCHEMBL25456787 | 0.97 | S1PR1 (0.49) | S1PR1S1PR3S1PR4S1PR5ALOX5 | |
| Ammonia Solution, Strong SCHEMBL25169992 | 0.96 | S1PR1 (0.48) | S1PR1S1PR3S1PR4S1PR5ALOX5 | |
| Ammonia Solution, Strong SCHEMBL25175635 | 0.94 | ALOX5 (0.52) | S1PR1S1PR3S1PR4S1PR5ALOX5 | |
| SCHEMBL25456753 | 0.94 | ALOX5 (0.52) | S1PR1S1PR3S1PR4S1PR5ALOX5 | |
| Ammonia Solution, Strong SCHEMBL25172939 | 0.93 | ALOX5 (0.51) | S1PR1S1PR3S1PR4S1PR5ALOX5 | |
| Ammonia Solution, Strong SCHEMBL25173211 | 0.92 | SLC2A1 (0.47) | S1PR1S1PR3S1PR4S1PR5ALOX5 | |
| SCHEMBL25456788 | 0.91 | ALOX5 (0.48) | S1PR1S1PR3S1PR4S1PR5ALOX5 | |
| SCHEMBL25456779 | 0.90 | SLC2A1 (0.51) | S1PR1S1PR3S1PR4S1PR5ALOX5 | |
| SCHEMBL25456761 | 0.89 | SLC2A1 (0.51) | S1PR1S1PR3ALOX5NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11802135-B2 | Lysophosphatidic acid derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2023-10-31 | — | — | US | disclosed |
| US-11802135-B2 | Lysophosphatidic acid derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2023-10-31 | — | — | US | disclosed |
| US-20230146210-A1 | NOVEL LYSOPHOSPHATIDIC ACID DERIVATIVE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2023-05-11 | — | — | US | disclosed |
| US-20230146210-A1 | NOVEL LYSOPHOSPHATIDIC ACID DERIVATIVE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11802135-B2 | Lysophosphatidic acid derivative | LPAR4, LPAR2, LPAR1 | S1PR1 32/4885S1PR3 27/4885S1PR4 12/4885 |
| US-20230146210-A1 | NOVEL LYSOPHOSPHATIDIC ACID DERIVATIVE | LPAR4, LPAR2, LPAR1 | S1PR1 31/4885S1PR3 25/4885S1PR4 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.