Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 20/20 | 0.71 |
| ▸ | TUBB | P07437 | 20/20 | 0.71 |
| ▸ | TUBA3C | P0DPH7 | 20/20 | 0.71 |
| ▸ | TUBA1B | P68363 | 20/20 | 0.71 |
| ▸ | TUBA4A | P68366 | 20/20 | 0.71 |
| ▸ | TUBB4B | P68371 | 20/20 | 0.71 |
| ▸ | TUBB3 | Q13509 | 20/20 | 0.71 |
| ▸ | TUBB2A | Q13885 | 20/20 | 0.71 |
| ▸ | TUBB8 | Q3ZCM7 | 20/20 | 0.71 |
| ▸ | TUBA3E | Q6PEY2 | 20/20 | 0.71 |
| ▸ | TUBA1A | Q71U36 | 20/20 | 0.71 |
| ▸ | TUBA1C | Q9BQE3 | 20/20 | 0.71 |
| ▸ | TUBB6 | Q9BUF5 | 20/20 | 0.71 |
| ▸ | TUBB2B | Q9BVA1 | 20/20 | 0.71 |
| ▸ | TUBB1 | Q9H4B7 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2551209 | 0.77 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10652522 | 0.74 | TUBB4A (0.66) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7062752 | 0.73 | TUBB4A (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4418601 | 0.73 | TUBB4A (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9050718 | 0.72 | MEN1 (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1307573 | 0.71 | TUBB4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5026223 | 0.71 | TUBB1 (0.87) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL786763 | 0.70 | EGFR (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1308179 | 0.70 | TUBB4A (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3743109 | 0.70 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121629-A1 | INDOLIC DERIVATIVES AND USE THEREOF IN MEDICAL FIELD | UNIVERSITA' DEGLI STUDI DL ROMA "LA SAPIENZA" (IT) | 2011-10-06 | — | — | WO | disclosed |
| WO-2011121629-A1 | INDOLIC DERIVATIVES AND USE THEREOF IN MEDICAL FIELD | UNIVERSITA' DEGLI STUDI DL ROMA "LA SAPIENZA" (IT) | 2011-10-06 | — | — | WO | disclosed |