SCHEMBL25458410

SCHEMBL25458410

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc5c4oc4ccc(-c6ccc(-c7ccccc7)c7c6sc6ccccc67)cc45)n3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 3/20 0.37
ALOX5 P09917 3/20 0.37
PIM1 P11309 1/20 0.36
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
PIM3 Q86V86 1/20 0.36
PIM2 Q9P1W9 1/20 0.36
PTPRF P10586 6/20 0.35
PTPN2 P17706 6/20 0.35
PTPN1 P18031 6/20 0.35
PRKDC P78527 2/20 0.33
MAPT P10636 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 1/20 0.32
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
PIK3CD O00329 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26225071 1.00 LIMK1 (0.37) LIMK1ALOX5PIM1CSNK2A2CSNK2B
SCHEMBL25458408 1.00 LIMK1 (0.37) LIMK1ALOX5PIM1CSNK2A2CSNK2B
SCHEMBL26762620 0.99 LIMK1 (0.38) LIMK1ALOX5PIM1CSNK2A2CSNK2B
SCHEMBL26214558 0.99 LIMK1 (0.38) LIMK1ALOX5PIM1CSNK2A2CSNK2B
SCHEMBL26225117 0.98 PIM1 (0.37) LIMK1ALOX5PIM1CSNK2A2CSNK2B
SCHEMBL26763211 0.97 PIM1 (0.36) LIMK1ALOX5PIM1CSNK2A2CSNK2B
SCHEMBL26221650 0.97 PIM1 (0.36) LIMK1ALOX5PIM1CSNK2A2CSNK2B
SCHEMBL24929386 0.95 ALOX5 (0.37) LIMK1ALOX5PIM1CSNK2A2CSNK2B
SCHEMBL26228634 0.94 ALOX5 (0.36) LIMK1ALOX5PIM1CSNK2A2CSNK2B
SCHEMBL26228691 0.94 ALOX5 (0.36) LIMK1ALOX5PIM1CSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357209-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-11-09 US disclosed
US-20230357209-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-11-09 US disclosed
US-20230157151-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230157151-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357209-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE CYP1A1, CYP1B1, ODC1 LIMK1 270/4885ALOX5 309/4885PIM1 1206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.