Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 2/20 | 0.54 |
| ▸ | JAK2 | O60674 | 3/20 | 0.51 |
| ▸ | CDK2 | P24941 | 5/20 | 0.49 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.49 |
| ▸ | FLT3 | P36888 | 2/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 3/20 | 0.46 |
| ▸ | SMG1 | Q96Q15 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CCNH | P51946 | 1/20 | 0.46 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2537277 | 0.88 | CAMK2D (0.56) | CAMK2DJAK2CDK2ACVR1CCNE1 | |
| SCHEMBL2544927 | 0.85 | JAK2 (0.56) | CAMK2DJAK2CDK2ACVR1CCNE1 | |
| SCHEMBL2539843 | 0.78 | ACVR1 (0.55) | CAMK2DJAK2CDK2ACVR1CCNE1 | |
| SCHEMBL2542794 | 0.78 | CAMK2D (0.56) | CAMK2DJAK2CDK2ACVR1CCNE1 | |
| SCHEMBL2547226 | 0.78 | FLT3 (0.67) | CAMK2DJAK2CDK2ACVR1CCNE1 | |
| SCHEMBL2546325 | 0.77 | CAMK2D (0.53) | CAMK2DJAK2CDK2ACVR1CCNE1 | |
| SCHEMBL2542950 | 0.76 | ACVR1 (0.61) | CAMK2DJAK2CDK2ACVR1CCNE1 | |
| SCHEMBL2547232 | 0.76 | JAK2 (0.52) | CAMK2DJAK2CDK2ACVR1CCNE1 | |
| SCHEMBL2227986 | 0.76 | CCNT1 (0.54) | CAMK2DJAK2CDK2ACVR1CCNE1 | |
| SCHEMBL2543915 | 0.76 | ACVR1 (0.53) | CAMK2DCDK2ACVR1CCNE1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263541-A1 | KINASE INHIBITORS AND THEIR USE AS PHARMACEUTICAL AGENTS | SHANGHAI GENOMICS, INC (CN) | 2011-10-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263541-A1 | KINASE INHIBITORS AND THEIR USE AS PHARMACEUTICAL AGENTS | MAP3K20, MAP3K1, MAP3K2 | CAMK2D 239/4885JAK2 178/4885CDK2 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.