Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 2/20 | 0.65 |
| ▸ | GRPR | P30550 | 2/20 | 0.65 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.56 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 4/20 | 0.53 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSH | P09668 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | GLP1R | P43220 | 5/20 | 0.51 |
| ▸ | CCKBR | P32239 | 2/20 | 0.51 |
| ▸ | GCGR | P47871 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25845909 | 0.90 | NMBR (0.66) | NMBRGRPRC5AR1IL23RF2 | |
| SCHEMBL25845917 | 0.90 | NMBR (0.66) | NMBRGRPRC5AR1IL23RF2 | |
| SCHEMBL31038378 | 0.89 | NMBR (0.63) | NMBRGRPRC5AR1F2GLP1R | |
| SCHEMBL25460022 | 0.88 | NMBR (0.63) | NMBRGRPRC5AR1IL23RF2 | |
| SCHEMBL30891928 | 0.88 | NMBR (0.63) | NMBRGRPRC5AR1IL23RF2 | |
| SCHEMBL14930601 | 0.84 | NMBR (0.58) | NMBRGRPRIL23RF2KISS1R | |
| SCHEMBL14930600 | 0.84 | NMBR (0.58) | NMBRGRPRIL23RF2KISS1R | |
| SCHEMBL25845686 | 0.84 | NMBR (0.58) | NMBRGRPRIL23RF2KISS1R | |
| SCHEMBL30567701 | 0.83 | C5AR1 (0.65) | NMBRGRPRC5AR1F2GLP1R | |
| SCHEMBL29557894 | 0.83 | C5AR1 (0.59) | NMBRGRPRC5AR1IL23RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023079142-A2 | TARGETED LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME | TARGIMMUNE THERAPEUTICS AG (CH) | 2023-05-11 | — | — | WO | disclosed |