Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30057746 | 1.00 | AKR1C3 (0.40) | AKR1C3AKR1C2APPFFAR4TRPV1 | |
| SCHEMBL25170241 | 0.90 | AKR1C3 (0.41) | AKR1C3AKR1C2APPPPARACETP | |
| SCHEMBL25170201 | 0.84 | ALOX5 (0.38) | TRPV1PPARAMRGPRX4EPHX2NR1H4 | |
| SCHEMBL30059779 | 0.84 | ALOX5 (0.38) | TRPV1PPARAMRGPRX4EPHX2NR1H4 | |
| SCHEMBL25168983 | 0.83 | AKR1C3 (0.55) | AKR1C3AKR1C2APPFFAR4 | |
| SCHEMBL25460886 | 0.83 | TRPV1 (0.36) | FFAR4TRPV1PPARAEPHX2NR1H4 | |
| SCHEMBL12079275 | 0.80 | APP (0.45) | AKR1C3AKR1C2APP | |
| SCHEMBL14498011 | 0.79 | TRPV1 (0.37) | TRPV1EPHX2NR1H4 | |
| SCHEMBL25464790 | 0.78 | EPHX2 (0.41) | EPHX2 | |
| SCHEMBL25173356 | 0.78 | APP (0.51) | AKR1C3AKR1C2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980325-A | Modulators of G-protein coupled receptors | 卡莫特治疗学股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | AKR1C3 3106/4885AKR1C2 2812/4885APP 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.