Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 6/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 3/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30603158 | 0.82 | IDO1 (0.49) | HDAC4SLC6A4SLC6A3SLC6A2CCR2 | |
| SCHEMBL29092831 | 0.82 | IDO1 (0.49) | HDAC4SLC6A4SLC6A3SLC6A2CCR2 | |
| SCHEMBL25460820 | 0.82 | HDAC4 (0.55) | HDAC4SLC6A4SLC6A3SLC6A2HDAC3 | |
| SCHEMBL25464568 | 0.81 | IDO1 (0.55) | HDAC4SLC6A4SLC6A3EP300CREBBP | |
| SCHEMBL25460818 | 0.81 | HDAC4 (0.73) | HDAC4HDAC1SMN1; SMN2 | |
| SCHEMBL29886254 | 0.81 | SLC6A4 (0.49) | HDAC4SLC6A4SLC6A3SLC6A2CCR2 | |
| SCHEMBL28595250 | 0.81 | SLC6A4 (0.49) | HDAC4SLC6A4SLC6A3SLC6A2CCR2 | |
| SCHEMBL3110960 | 0.81 | AKR1C1 (0.65) | HDAC4SLC6A4SLC6A3SLC6A2CCR2 | |
| SCHEMBL12880247 | 0.81 | ALDH1A1 (0.56) | HDAC4SLC6A4SLC6A3SLC6A2CCR2 | |
| SCHEMBL16639040 | 0.80 | HDAC4 (0.71) | HDAC4HDAC1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | HDAC4 2192/4885SLC6A4 1150/4885SLC6A3 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.