SCHEMBL25463591

SCHEMBL25463591

Clc1ccc(-c2ccncc2)cc1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
LMNA P02545 1/20 0.46
QDPR P09417 1/20 0.45
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
AHR P35869 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HTT P42858 1/20 0.41
AAK1 Q2M2I8 1/20 0.40
NPY5R Q15761 1/20 0.40
NOTUM Q6P988 1/20 0.39
PDE3B Q13370 1/20 0.39
PDE3A Q14432 1/20 0.39
DYRK1A Q13627 1/20 0.39
KIF11 P52732 2/20 0.39
P2RX7 Q99572 1/20 0.38
GCGR P47871 2/20 0.38
ERN1 O75460 1/20 0.38
CLK1 P49759 1/20 0.38
MAPK14 Q16539 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26805871 0.80 AHR (0.46) LMNANPC1RAB9AAHRSMN1; SMN2
SCHEMBL457778 0.78 ESR2 (0.52) MAPTLMNAAHRHTT
SCHEMBL29921215 0.78 ESR2 (0.52) MAPTLMNAAHRHTT
SCHEMBL25463021 0.77 CYP11B1 (0.56) MAPTLMNASMN1; SMN2HTTNPY5R
SCHEMBL30510018 0.77 AHR (0.42) NPC1RAB9AAHRSMN1; SMN2
SCHEMBL25296559 0.77 AHR (0.42) NPC1RAB9AAHRSMN1; SMN2
SCHEMBL16371285 0.75 AAK1 (0.58) MAPTLMNAQDPRSMN1; SMN2HTT
SCHEMBL23604537 0.72 ALDH1A1 (0.50) AHRKIF11
SCHEMBL8324614 0.72 ERN1 (0.61) MAPTLMNAQDPRAAK1PDE3B
SCHEMBL7282401 0.72 PIK3CD (0.50) MAPTLMNAPDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023085637-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-05-19 WO disclosed