Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814047 | 0.78 | KDM4E (0.53) | KDM4EKMT2ACA1CA2ACHE | |
| SCHEMBL11527808 | 0.77 | PTGDR2 (0.42) | HTR2CPOLLMEN1KMT2AADRA2A | |
| SCHEMBL1515163 | 0.77 | HTR2C (0.75) | HTR2CDRD2MEN1KMT2ACA1 | |
| Bromide SCHEMBL28922144 | 0.76 | KDM4E (0.51) | KDM4EKMT2ACA1CA2ACHE | |
| SCHEMBL12964269 | 0.76 | HTR2C (0.53) | HTR2CPOLLDRD2MEN1KMT2A | |
| SCHEMBL16577518 | 0.76 | ABCB1 (0.57) | HTR2CPOLLDRD2MEN1KMT2A | |
| SCHEMBL18790124 | 0.76 | HTR2C (0.46) | HTR2CMEN1KMT2ACA1CA2 | |
| SCHEMBL29639264 | 0.76 | HTR2C (0.53) | HTR2CPOLLDRD2KDM4EMEN1 | |
| Methyl Alcohol SCHEMBL27577395 | 0.74 | KDM4E (0.54) | KDM4EKMT2ACA1CA2ACHE | |
| Chloromethane SCHEMBL27930402 | 0.74 | KDM4E (0.50) | KDM4EKMT2ACA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083297-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-19 | — | — | WO | disclosed |