Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | RAF1 | P04049 | 4/20 | 0.57 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.54 |
| ▸ | CASR | P41180 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475260 | 0.82 | EPHX2 (0.66) | EPHX2KDRRAF1GAAMAPT | |
| SCHEMBL12475138 | 0.82 | EPHX2 (0.66) | EPHX2KDRRAF1GAAMAPT | |
| SCHEMBL15612788 | 0.82 | EPHX2 (0.66) | EPHX2KDRRAF1GAAMAPT | |
| SCHEMBL30571077 | 0.82 | EPHX2 (0.66) | EPHX2KDRRAF1GAAMAPT | |
| SCHEMBL31757108 | 0.81 | KDR (0.68) | EPHX2KDRRAF1GAAMAPT | |
| SCHEMBL28508800 | 0.79 | EPHX2 (0.65) | EPHX2KDRRAF1GAAMAPT | |
| SCHEMBL25464474 | 0.79 | EPHX2 (0.66) | EPHX2MAPTKMT2A | |
| SCHEMBL25464505 | 0.79 | ALDH1A1 (0.60) | EPHX2PRMT3KMT2ASMN1; SMN2 | |
| SCHEMBL21499267 | 0.78 | EPHX2 (0.70) | EPHX2KDRRAF1GAAMAPT | |
| SCHEMBL31125108 | 0.78 | EPHX2 (0.67) | EPHX2KDRRAF1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | EPHX2 3721/4885KDR 1753/4885RAF1 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.