⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25465289 | 1.00 | — | — | |
| SCHEMBL25465288 | 1.00 | — | — | |
| SCHEMBL25464266 | 1.00 | — | — | |
| SCHEMBL25464272 | 1.00 | — | — | |
| SCHEMBL679278 | 0.87 | MEN1 (0.32) | — | |
| SCHEMBL478333 | 0.84 | ALDH1A1 (0.31) | — | |
| SCHEMBL16247767 | 0.80 | — | — | |
| SCHEMBL25465562 | 0.77 | — | — | |
| SCHEMBL25465515 | 0.77 | — | — | |
| SCHEMBL22456319 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230147458-A1 | IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | JANSSEN RESEARCH & DEVELOPMENT, LLC | 2023-05-11 | — | — | US | disclosed |
| US-20230143050-A1 | IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | JANSSEN RESEARCH & DEVELOPMENT, LLC | 2023-05-11 | — | — | US | disclosed |