Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.47 |
| ▸ | MET | P08581 | 5/20 | 0.47 |
| ▸ | AURKA | O14965 | 4/20 | 0.47 |
| ▸ | TEK | Q02763 | 4/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 5/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24028624 | 1.00 | KDR (0.47) | KDRMETAURKATEKAURKB | |
| SCHEMBL24028651 | 0.97 | KDR (0.45) | KDRMETAURKATEKAURKB | |
| SCHEMBL24028874 | 0.91 | MET (0.42) | KDRMETAURKATEKAURKB | |
| SCHEMBL24028648 | 0.88 | MET (0.43) | KDRMETAURKATEKAURKB | |
| SCHEMBL24028348 | 0.88 | MET (0.43) | KDRMETAURKATEKAURKB | |
| SCHEMBL24028350 | 0.88 | MET (0.43) | KDRMETAURKATEKAURKB | |
| SCHEMBL24028342 | 0.88 | KDR (0.46) | KDRMETAURKATEKAURKB | |
| SCHEMBL24028343 | 0.86 | KDR (0.48) | KDRMETAURKATEKAURKB | |
| SCHEMBL25465678 | 0.86 | KDR (0.48) | KDRMETAURKATEKAURKB | |
| SCHEMBL24028631 | 0.86 | KDR (0.53) | KDRMETAURKATEKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086638-A1 | ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |