Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22794389 | 0.96 | PAOX (0.47) | ALDH1A1TSHRPAOXS1PR2S1PR4 | |
| SCHEMBL18660081 | 0.88 | DNM1 (0.50) | ALDH1A1TSHRS1PR2S1PR1S1PR3 | |
| SCHEMBL16658679 | 0.88 | DNM1 (0.50) | ALDH1A1TSHRS1PR2S1PR1S1PR3 | |
| SCHEMBL4601205 | 0.88 | DNM1 (0.50) | ALDH1A1TSHRS1PR2S1PR1S1PR3 | |
| SCHEMBL2180094 | 0.88 | DNM1 (0.50) | ALDH1A1TSHRS1PR2S1PR1S1PR3 | |
| SCHEMBL16658678 | 0.88 | DNM1 (0.50) | ALDH1A1TSHRS1PR2S1PR1S1PR3 | |
| SCHEMBL6949703 | 0.88 | DNM1 (0.50) | ALDH1A1TSHRS1PR2S1PR1S1PR3 | |
| SCHEMBL3440790 | 0.88 | DNM1 (0.50) | ALDH1A1TSHRS1PR2S1PR1S1PR3 | |
| SCHEMBL1902069 | 0.88 | DNM1 (0.50) | ALDH1A1TSHRS1PR2S1PR1S1PR3 | |
| SCHEMBL16658724 | 0.88 | DNM1 (0.50) | ALDH1A1TSHRS1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081759-A1 | BIFUNCTIONAL PI3K-ALPHA INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| US-20230132715-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230132715-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | ALDH1A1 2776/4885TSHR 3319/4885PAOX 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.