⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13598143 | 1.00 | — | — | |
| SCHEMBL2546862 | 1.00 | — | — | |
| SCHEMBL166635 | 1.00 | — | — | |
| SCHEMBL166636 | 1.00 | — | — | |
| SCHEMBL15809890 | 0.84 | GABRP (0.45) | — | |
| SCHEMBL15809891 | 0.84 | GABRP (0.45) | — | |
| SCHEMBL43207 | 0.79 | — | — | |
| SCHEMBL12714083 | 0.79 | — | — | |
| SCHEMBL5355929 | 0.79 | GABRP (0.36) | — | |
| SCHEMBL2915536 | 0.79 | GABRP (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228505-A1 | BICYCLIC PYRIDINE DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2024-07-11 | — | — | US | disclosed |
| US-20240150370-A1 | BICYCLIC PYRIDINE DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2024-05-09 | — | — | US | disclosed |
| EP-4324834-A1 | BICYCLIC PYRIDINE DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2024-02-21 | — | — | EP | disclosed |
| CN-117177977-A | Bicyclic pyridine derivatives | 住友制药株式会社 | 2023-12-05 | — | — | CN | disclosed |
| US-20120330030-A1 | Enantioselective Synthesis of y-amino-a, B-unsuturated carboxylic acid derivatives | ACEMOGLU MURAT (CH) | 2012-12-27 | — | — | US | disclosed |
| US-8288566-B2 | Enantioselective synthesis of γ-amino-αβ-unsaturated carboxylic acid derivatives | NOVARTIS AG (CH) | 2012-10-16 | — | — | US | disclosed |
| US-20110263873-A1 | Enantioselective Synthesis of y-amino-alpha beta-unsaturated carboxylic acid derivatives | NOVARTIS AG (CH) | 2011-10-27 | — | — | US | disclosed |