Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.33 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24005739 | 0.86 | MAPT (0.33) | BRD4CDK8FGFR1KDRAXL | |
| SCHEMBL24005699 | 0.82 | BRD4 (0.41) | ALOX5APFEN1BRD4CDK8FGFR1 | |
| SCHEMBL25613036 | 0.77 | FEN1 (0.36) | TTKALOX5APFEN1BRD4CDK8 | |
| SCHEMBL24005904 | 0.76 | CDK8 (0.39) | FEN1BRD4CDK8FGFR1KDR | |
| SCHEMBL24005901 | 0.73 | PIK3CA (0.36) | BRD4CDK8FGFR1KDRAXL | |
| SCHEMBL24005768 | 0.70 | CHRNB2 (0.39) | — | |
| SCHEMBL28802433 | 0.68 | MEN1 (0.35) | — | |
| SCHEMBL13021082 | 0.68 | BRD4 (0.40) | ALOX5APFEN1BRD4CDK8TTBK1 | |
| SCHEMBL22560747 | 0.68 | KDR (0.49) | BRD4CDK8TTBK1TTBK2FGFR1 | |
| SCHEMBL25650900 | 0.68 | LPAR1 (0.33) | BRD4CDK8FGFR1KDRAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078398-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2023-05-11 | — | — | WO | disclosed |