⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860617 | 0.88 | — | — | |
| SCHEMBL12454538 | 0.78 | ALDH1A1 (0.32) | — | |
| SCHEMBL1431864 | 0.69 | — | — | |
| SCHEMBL232122 | 0.69 | — | — | |
| SCHEMBL447169 | 0.67 | — | — | |
| SCHEMBL7934289 | 0.65 | — | — | |
| SCHEMBL565055 | 0.65 | — | — | |
| SCHEMBL9989026 | 0.61 | — | — | |
| SCHEMBL73117 | 0.61 | — | — | |
| SCHEMBL621262 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4628060-A | Fungicidal tetrahydrothiopyran-3,5-dione derivatives, intermediate derivatives, compositions, and method of use therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-09 | — | — | US | claimed |
| EP-0126380-A1 | Substituted tetrahydrothiopyran-3,5-dione-4-carboxamide | BAYER AG (DE) | 1984-11-28 | — | — | EP | claimed |
| JP-3038586-A | — | — | None | — | — | JP | disclosed |
| EP-4713320-A2 | BCAT2 INHIBITORS | Agios Pharmaceuticals, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024238820-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| EP-4430036-A2 | BCAT2 INHIBITORS | Agios Pharmaceuticals, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| US-20240228504-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-11 | — | — | US | disclosed |
| US-20240228504-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-11 | — | — | US | disclosed |
| US-20240228504-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-11 | — | — | US | disclosed |
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230303489-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS INC (US) | 2023-09-28 | — | — | US | disclosed |
| US-4695673-A | Process for the production of acylated 1,3-dicarbonyl compounds | STAUFFER CHEMICAL COMPANY (US) | 1987-09-22 | — | — | US | disclosed |
| US-4628060-A | Fungicidal tetrahydrothiopyran-3,5-dione derivatives, intermediate derivatives, compositions, and method of use therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-09 | — | — | US | disclosed |
| US-4628060-A | Fungicidal tetrahydrothiopyran-3,5-dione derivatives, intermediate derivatives, compositions, and method of use therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-09 | — | — | US | disclosed |
| EP-0126380-A1 | Substituted tetrahydrothiopyran-3,5-dione-4-carboxamide | BAYER AG (DE) | 1984-11-28 | — | — | EP | disclosed |
| EP-0126380-A1 | Substituted tetrahydrothiopyran-3,5-dione-4-carboxamide | BAYER AG (DE) | 1984-11-28 | — | — | EP | disclosed |
| US-4441911-A | PRE- AND POST-EMERGENCE | SHELL OIL COMPANY (US) | 1984-04-10 | — | — | US | disclosed |
| EP-0018368-B1 | INSECTICIDAL 2-SUBSTITUTED-IMINO-3-ALKYL-5-DIALKOXYPHOSPHINOTHIOYLOXY-6H-1, 3,4-THIADIAZINES AND PREPARATION THEREOF | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1982-06-16 | — | — | EP | disclosed |
| US-4130565-A | 3-ALKYL-TETRAHYDROPYRAN-OR THIOPYRAN-2,4-DIONES AS CHEMICAL INTERMEDIATES | SHIONOGI & CO., LTD. (JP) | 1978-12-19 | — | — | US | disclosed |
| US-4083852-A | ORAL CONTRACEPTIVES | SHIONOGI & CO., LTD. (JA) | 1978-04-11 | — | — | US | disclosed |