Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 15/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 14/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15633560 | 0.89 | CYP3A4 (0.51) | CYP3A4CYP2D6 | |
| SCHEMBL15633881 | 0.89 | CYP3A4 (0.51) | CYP3A4CYP2D6 | |
| SCHEMBL15634070 | 0.89 | CYP3A4 (0.51) | CYP3A4CYP2D6 | |
| SCHEMBL15633489 | 0.89 | CYP3A4 (0.51) | CYP3A4CYP2D6 | |
| SCHEMBL15633919 | 0.89 | CYP3A4 (0.51) | CYP3A4CYP2D6 | |
| SCHEMBL21318454 | 0.86 | CYP3A4 (0.53) | CYP3A4CYP2D6 | |
| SCHEMBL21318428 | 0.85 | CYP3A4 (0.47) | CYP3A4CYP2D6ATM | |
| SCHEMBL21318447 | 0.85 | CYP3A4 (0.54) | CYP3A4CYP2D6 | |
| SCHEMBL21318448 | 0.85 | CYP3A4 (0.47) | CYP3A4CYP2D6ATM | |
| SCHEMBL15633920 | 0.79 | CYP3A4 (0.51) | CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940313-B2 | Tyrosine-based prodrugs of antiviral agents | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940313-B2 | Tyrosine-based prodrugs of antiviral agents | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940313-B2 | Tyrosine-based prodrugs of antiviral agents | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-01-27 | — | — | US | disclosed |
| US-20110263535-A1 | TYROSINE-BASED PRODRUGS OF ANTIVIRAL AGENTS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2011-10-27 | — | — | US | disclosed |
| US-20110263535-A1 | TYROSINE-BASED PRODRUGS OF ANTIVIRAL AGENTS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2011-10-27 | — | — | US | disclosed |
| US-20110263535-A1 | TYROSINE-BASED PRODRUGS OF ANTIVIRAL AGENTS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2011-10-27 | — | — | US | disclosed |
| WO-2011133963-A2 | TYROSINE-BASED PRODRUGS OF ANTIVIRAL AGENTS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2011-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263535-A1 | TYROSINE-BASED PRODRUGS OF ANTIVIRAL AGENTS | TYMP, MTAP, TK1 | CYP3A4 1593/4885CYP2D6 1076/4885ATM 1896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.