⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053378 | 0.92 | — | — | |
| SCHEMBL5712172 | 0.91 | ALDH1A1 (0.65) | — | |
| SCHEMBL8465379 | 0.90 | ALDH1A1 (0.64) | — | |
| SCHEMBL27508617 | 0.90 | ALDH1A1 (0.64) | — | |
| SCHEMBL8465180 | 0.89 | ALDH1A1 (0.52) | — | |
| Methylene Chloride SCHEMBL1421250 | 0.88 | ALDH1A1 (0.56) | — | |
| SCHEMBL25841567 | 0.86 | ALDH1A1 (0.44) | — | |
| SCHEMBL56801 | 0.83 | — | — | |
| SCHEMBL8268591 | 0.80 | — | — | |
| SCHEMBL28616847 | 0.78 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775165-A | Multi-phase force stimulus response luminescent material and preparation and application thereof | 中国航发商用航空发动机有限责任公司 | 2025-04-08 | — | — | CN | claimed |
| EP-1569925-A1 | 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2005-09-07 | — | — | EP | claimed |
| WO-2004055003-A1 | 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2004-07-01 | — | — | WO | claimed |
| US-20250388615-A9 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | ARDELYX, INC. (US) | 2025-12-25 | — | — | US | disclosed |
| EP-4578451-A2 | COMPOUNDS AND COMPOSITIONS AS SPPL2A INHIBITORS | Novartis AG (CH) | 2025-07-02 | — | — | EP | disclosed |
| EP-4214210-B1 | COMPOUNDS AND COMPOSITIONS AS SPPL2A INHIBITORS | NOVARTIS AG (CH) | 2025-04-09 | — | — | EP | disclosed |
| CN-119775165-A | Multi-phase force stimulus response luminescent material and preparation and application thereof | 中国航发商用航空发动机有限责任公司 | 2025-04-08 | — | — | CN | disclosed |
| US-20250066410-A1 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | ARDELYX, INC. (US) | 2025-02-27 | — | — | US | disclosed |
| US-12084472-B2 | Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists | ARDELYX, INC. (US) | 2024-09-10 | — | — | US | disclosed |
| CN-114245796-B | Imidazo [1,2-a ] pyridinyl derivatives and their use in the treatment of diseases | 比奥根MA公司 | 2024-07-30 | — | — | CN | disclosed |
| US-20230365571-A1 | COMPOUNDS AND COMPOSITIONS AS Sppl2a INHIBITORS | NOVARTIS AG (CH) | 2023-11-16 | — | — | US | disclosed |
| US-20010037033-A1 | Method for producing axial asymmetric compounds, intermediates for producing the same, complexes of transition metals with novel axial asymmetric compounds as the ligands, catalysts for asymmetric hydrogenation, and catalysts for forming asymmetric carbon-carbon bonds | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-11-01 | — | — | US | disclosed |
| EP-1013658-A1 | Aminophosphine-metal complex for asymmetric reactions | Takasago International Corporation (JP) | 2000-06-28 | — | — | EP | disclosed |
| EP-0193148-A2 | 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(alkoxy-containing acyl)hydrazides | G.D. Searle & Co. (US) | 1986-09-03 | — | — | EP | disclosed |
| US-4590209-A | INOTROPIC, ANTIARRHYTHMIA, AND ANTILIPEMIC AGENTS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1986-05-20 | — | — | US | disclosed |
| US-4559337-A | 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(alkoxy-containing acyl)hydrazides | G.D. SEARLE & CO. (US) | 1985-12-17 | — | — | US | disclosed |
| US-4327034-A | CHEMICAL INTERMEDIATE PREPARED FROM A SULFAMIC ACID HALIDE AND A HALOGEN COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1982-04-27 | — | — | US | disclosed |
| EP-0017074-A1 | Process and intermediates for preparing 11-(alkoxy- and alkylmercapto-3-oxoalkyl)-2,6-methano-3-benzazocines | STERLING DRUG INC. (US) | 1980-10-15 | — | — | EP | disclosed |
| US-4202983-A | 11-(Lower-alkoxy- and lower-alkylthio-3-oxo-lower-alkyl)-hexahydro-2,6-m ethano-benzazocines | STERLING DRUG INC. (US) | 1980-05-13 | — | — | US | disclosed |
| EP-0007439-A1 | Sulphamic acid halides and method for their preparation | BASF Aktiengesellschaft (DE) | 1980-02-06 | — | — | EP | disclosed |