Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12308339 | 0.77 | SLC22A2 (0.32) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL13126723 | 0.77 | SLC22A2 (0.32) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL18781236 | 0.76 | — | — | |
| SCHEMBL21427331 | 0.76 | APLNR (0.42) | — | |
| SCHEMBL25474668 | 0.74 | — | — | |
| SCHEMBL25779211 | 0.72 | APLNR (0.32) | — | |
| SCHEMBL12308341 | 0.70 | MEN1 (0.41) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL25005434 | 0.70 | — | — | |
| SCHEMBL25005225 | 0.70 | — | — | |
| SCHEMBL25419059 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078319-A1 | HETEROCYCLIC COMPOUND CAPABLE OF INHIBITING IL-17A AND USE OF HETEROCYCLIC COMPOUND | 海思科医药集团股份有限公司 | 2023-05-11 | — | — | WO | disclosed |