SCHEMBL25475593

SCHEMBL25475593

CC(=O)OCC1OC(OC(C)=O)C(NC(=O)c2ccc(C(=C(c3ccccc3)c3ccccc3)c3ccccc3)cc2)C(C)C1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
KMT2A Q03164 1/20 0.48
TRIP13 Q15645 2/20 0.44
TSHR P16473 1/20 0.42
KDM4E B2RXH2 1/20 0.40
TGM2 P21980 1/20 0.39
POLB P06746 2/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP3A4 P08684 2/20 0.38
MAPT P10636 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2D6 P10635 1/20 0.38
CA12 O43570 6/20 0.38
CA1 P00915 6/20 0.38
CA2 P00918 6/20 0.38
CA9 Q16790 4/20 0.38
CA14 Q9ULX7 4/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP2C19 P33261 1/20 0.37
LGALS9 O00182 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25476273 0.88 LMNA (0.68) LMNAKMT2ATRIP13TSHRKDM4E
SCHEMBL17527987 0.83 LMNA (0.73) LMNAKMT2ATRIP13TSHRKDM4E
SCHEMBL7152558 0.83 LMNA (0.73) LMNAKMT2ATRIP13TSHRKDM4E
SCHEMBL3393349 0.83 LMNA (0.73) LMNAKMT2ATRIP13TSHRKDM4E
SCHEMBL20207077 0.83 LMNA (0.73) LMNAKMT2ATRIP13TSHRKDM4E
SCHEMBL7152557 0.83 LMNA (0.73) LMNAKMT2ATRIP13TSHRKDM4E
SCHEMBL17527862 0.83 LMNA (0.73) LMNAKMT2ATRIP13TSHRKDM4E
SCHEMBL20202228 0.83 LMNA (0.73) LMNAKMT2ATRIP13TSHRKDM4E
SCHEMBL20202226 0.83 LMNA (0.73) LMNAKMT2ATRIP13TSHRKDM4E
SCHEMBL20202239 0.83 LMNA (0.73) LMNAKMT2ATRIP13TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230151270-A1 Aggregation-Induced Emission Polymer, Preparation Method and Application Thereof QINGDAO AGRICULTURAL UNIVERSITY (CN) 2023-05-18 US disclosed