Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | BMP1 | P13497 | 1/20 | 0.31 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25476841 | 0.97 | F2 (0.33) | ACERENF2BMP1VSIR | |
| SCHEMBL25476845 | 0.94 | VSIR (0.31) | F2BMP1VSIRCD274DPP4 | |
| SCHEMBL25476870 | 0.94 | F2 (0.32) | F2BMP1VSIRCD274DPP4 | |
| SCHEMBL21168299 | 0.94 | ACE (0.36) | ACERENF2BMP1DPP4 | |
| SCHEMBL21168320 | 0.94 | ACE (0.36) | ACERENF2BMP1DPP4 | |
| SCHEMBL31489982 | 0.94 | ACE (0.36) | ACERENF2BMP1DPP4 | |
| SCHEMBL31490055 | 0.93 | ACE (0.36) | ACERENF2BMP1DPP4 | |
| SCHEMBL25476866 | 0.93 | VSIR (0.33) | F2BMP1VSIRCD274 | |
| SCHEMBL21168341 | 0.92 | PEPD (0.33) | ACERENBMP1DPP4 | |
| SCHEMBL21168339 | 0.92 | PEPD (0.33) | ACERENBMP1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144653-A1 | 1,2,4-Oxadiazole Compounds as Inhibitors of CD47 Signalling Pathways | AURIGENE ONCOLOGY LIMITED (IN) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230144653-A1 | 1,2,4-Oxadiazole Compounds as Inhibitors of CD47 Signalling Pathways | CD47, HIF1AN, PIK3R5 | ACE 4811/4885REN 4143/4885F2 4693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.