Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2539872 | 0.83 | TP53 (0.41) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL599852 | 0.82 | TP53 (0.39) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL2454623 | 0.80 | TP53 (0.47) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL859860 | 0.80 | TP53 (0.42) | TP53OPRM1CA1LAP3 | |
| SCHEMBL1343885 | 0.80 | TP53 (0.38) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL27471627 | 0.80 | TP53 (0.38) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL2715230 | 0.79 | TP53 (0.41) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL11881434 | 0.78 | NR1I2 (0.38) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL27872723 | 0.78 | TP53 (0.37) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL27553098 | 0.78 | TP53 (0.37) | TP53ADH1BADH1CADH1AADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101415732-A | Aryl/alkyl vinyl sulfone hyaluronic acid derivatives | NOVOZYMES BIOPOLYMER AS (DK) | 2009-04-22 | — | — | CN | claimed |
| US-8071757-B2 | Aryl/alkyl vinyl sulfone hyaluronic acid derivatives | NOVOZYMES BIOPHARMA DK A/S (DK) | 2011-12-06 | — | — | US | disclosed |
| US-20110257123-A1 | ARYL/ALKYL VINYL SULFONE HYALURONIC ACID DERIVATIVES | NOVOZYMES BIOPOLYMER A/S (NL) | 2011-10-20 | — | — | US | disclosed |
| US-20110257123-A1 | ARYL/ALKYL VINYL SULFONE HYALURONIC ACID DERIVATIVES | NOVOZYMES BIOPOLYMER A/S (NL) | 2011-10-20 | — | — | US | disclosed |
| CN-101415732-B | Aryl/alkyl vinyl sulfone hyaluronic acid derivatives | NOVOZYMES BIOPOLYMER AS | 2011-10-12 | — | — | CN | disclosed |
| CN-101415732-B | Aryl/alkyl vinyl sulfone hyaluronic acid derivatives | NOVOZYMES BIOPOLYMER AS | 2011-10-12 | — | — | CN | disclosed |
| EP-1994062-B1 | ARYL/ALKYL VINYL SULFONE HYALURONIC ACID DERIVATIVES | NOVOZYMES BIOPOLYMER AS (DK) | 2009-07-15 | — | — | EP | disclosed |
| EP-1994062-B1 | ARYL/ALKYL VINYL SULFONE HYALURONIC ACID DERIVATIVES | NOVOZYMES BIOPOLYMER AS (DK) | 2009-07-15 | — | — | EP | disclosed |
| CN-101415732-A | Aryl/alkyl vinyl sulfone hyaluronic acid derivatives | NOVOZYMES BIOPOLYMER AS (DK) | 2009-04-22 | — | — | CN | disclosed |
| CN-101415732-A | Aryl/alkyl vinyl sulfone hyaluronic acid derivatives | NOVOZYMES BIOPOLYMER AS (DK) | 2009-04-22 | — | — | CN | disclosed |
| EP-1994062-A1 | ARYL/ALKYL VINYL SULFONE HYALURONIC ACID DERIVATIVES | Novozymes Biopolymer A/S (DK) | 2008-11-26 | — | — | EP | disclosed |
| EP-1994062-A1 | ARYL/ALKYL VINYL SULFONE HYALURONIC ACID DERIVATIVES | Novozymes Biopolymer A/S (DK) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007098770-A1 | ARYL/ALKYL VINYL SULFONE HYALURONIC ACID DERIVATIVES | NOVOZYMES BIOPOLYMER A/S (DK) | 2007-09-07 | — | — | WO | disclosed |
| WO-2007098770-A1 | ARYL/ALKYL VINYL SULFONE HYALURONIC ACID DERIVATIVES | NOVOZYMES BIOPOLYMER A/S (DK) | 2007-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257123-A1 | ARYL/ALKYL VINYL SULFONE HYALURONIC ACID DERIVATIVES | CD44, ARSA, HPSE | TP53 1088/4885ADH1B 554/4885ADH1C 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.