SCHEMBL2454623

SCHEMBL2454623

C=CC(CCCCC)S(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.47
FDPS P14324 4/20 0.36
MAPT P10636 2/20 0.36
ZDHHC20 Q5W0Z9 2/20 0.36
ZDHHC2 Q9UIJ5 2/20 0.36
TRPA1 O75762 1/20 0.36
DDAH1 O94760 1/20 0.36
GAPDH P04406 1/20 0.36
GPR84 Q9NQS5 4/20 0.35
CA1 P00915 2/20 0.35
FFAR1 O14842 1/20 0.35
LMNA P02545 1/20 0.34
LAP3 P28838 1/20 0.34
LCK P06239 1/20 0.34
PPARD Q03181 1/20 0.34
ADH1B P00325 1/20 0.33
ADH1C P00326 1/20 0.33
ADH1A P07327 1/20 0.33
ADH4 P08319 1/20 0.33
ADH7 P40394 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28007248 0.98 TP53 (0.46) TP53FDPSMAPTZDHHC20ZDHHC2
SCHEMBL4563719 0.94 TP53 (0.39) TP53FDPSZDHHC20ZDHHC2CA1
SCHEMBL28834696 0.92 TP53 (0.38) TP53FDPSZDHHC20ZDHHC2CA1
SCHEMBL8387816 0.85 HDAC1 (0.36) TP53FDPSCA1
SCHEMBL2539872 0.83 TP53 (0.41) TP53FDPSMAPTZDHHC20ZDHHC2
SCHEMBL599852 0.82 TP53 (0.39) TP53FDPSMAPTZDHHC20ZDHHC2
SCHEMBL14955824 0.80 SLC6A2 (0.30)
SCHEMBL1343885 0.80 TP53 (0.38) TP53FDPSMAPTZDHHC20ZDHHC2
SCHEMBL859860 0.80 TP53 (0.42) TP53CA1LAP3
SCHEMBL2547722 0.80 TP53 (0.38) TP53FDPSMAPTZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10344143-B2 Method for providing resistance to yellowing in polyamide articles and polyamide articles obtained from this method RHODIA POLIAMIDA E ESPECIALIDADES S.A. (BR) 2019-07-09 US claimed
US-20170335087-A1 Method for providing resistance to yellowing in polyamide articles and polyamide articles obtained from this method RHODIA POLIAMIDA E ESPECIALIDADES LTDA (BR) 2017-11-23 US claimed
CN-102186862-B The composition and method of lecithin and plasticizer 阿彻丹尼尔斯米德兰德公司 2017-10-17 CN claimed
EP-3227375-A1 METHOD FOR PROVIDING RESISTANCE TO YELLOWING IN POLYAMIDE ARTICLES AND POLYAMIDE ARTICLES OBTAINED FROM THIS METHOD Rhodia Poliamida E Especialidades Ltda (BR) 2017-10-11 EP claimed
WO-2016087913-A1 METHOD FOR PROVIDING RESISTANCE TO YELLOWING IN POLYAMIDE ARTICLES AND POLYAMIDE ARTICLES OBTAINED FROM THIS METHOD RHODIA POLIAMIDA E ESPECIALIDADES LTDA (BR) 2016-06-09 WO claimed
US-7678937-B2 Polyalkylated arylalkyl sulfonic acids and their salts BERGER PAUL DANIEL 2010-03-16 US claimed
US-7605287-B2 Polyalkylated arylalkyl sulfonic acids and their salts OIL CHEM TECHNOLOGIES (US) 2009-10-20 US claimed
US-20090249555-A1 METHOD OF PREVENTING YELLOWING IN FABRICS AND GARMENTS INVISTA NORTH AMERICA S.A R.L. (US) 2009-10-08 US claimed
US-20090032461-A1 METHOD FOR SEPARATING POLYMER SYSTEMS AND PORE-FREE POLYMER FILMS USED IN SAID METHOD PHILIPPS-UNIVERSITAT MARBURG (DE) 2009-02-05 US claimed
US-20090023950-A1 Polyalkylated arylalkyl sulfonic acids and their salts OIL CHEM TECHNOLOGIES, INC. (US) 2009-01-22 US claimed
US-20090023951-A1 Polyalkylated Arylalkyl Sulfonic acids and their salts BERGER PAUL DANIEL 2009-01-22 US claimed
CN-101130940-A Moisture-proof flame-retardant liquid specially adapted to corrugated paper box DONGJING CONTROL GROUP (CN) 2008-02-27 CN claimed
US-20050239808-A1 Active substances for the treatment, diagnosis and prophylaxis of diseases in which abnormal protein structures occur TRANSMIT GESELLSCHAFT FUR TECHNOLOGIETRANSFER MBH (DE) 2005-10-27 US claimed
EP-1503990-A1 ACTIVE SUBSTANCES FOR THE TREATMENT, DIAGNOSIS AND PROPHYLAXIS OF DISEASES IN WHICH ABNORMAL PROTEIN STRUCTURES OCCUR Transmit Gesellschaft für Technologietransfer mbH (DE) 2005-02-09 EP claimed
WO-2003095429-A1 ACTIVE SUBSTANCES FOR THE TREATMENT, DIAGNOSIS AND PROPHYLAXIS OF DISEASES IN WHICH ABNORMAL PROTEIN STRUCTURES OCCUR TransMIT Gesellschaft für Technologietransfer mbH (DE) 2003-11-20 WO claimed
US-5646103-A OF A BIODEGRADABLE TERPOLYMER, A WATER CONTAINING ZEOLITE AND A CRYSTALLINE LAYER SILICATE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1997-07-08 US claimed
US-4731389-A POLYVINYL ALCOHOL AIR KRETE, INC. (US) 1988-03-15 US claimed
CN-108779557-B Corrosion inhibiting compositions for reducing corrosion in environments containing elemental sulfur and/or polysulfides 艺康美国股份有限公司 2020-12-25 CN disclosed
US-3952105-A TRIORGANO-STANNOXY SUBSTITUTED 6B METAL ESTER SCM CORPORATION (US) 1976-04-20 US disclosed
US-3936375-A Process for dewatering a proteinaceous, aqueous sludge and for removing and recovering precipitating agents from a precipitate containing proteinaceous substances A/S APOTHEKERNES LABORATORIUM FOR SPECIALPRAEPARATER (NO) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090023950-A1 Polyalkylated arylalkyl sulfonic acids and their salts HRH3, PAH, KCNH3 TP53 4227/4885FDPS 2384/4885MAPT 4721/4885
US-20050239808-A1 Active substances for the treatment, diagnosis and prophylaxis of diseases in which abnormal protein structures occur PRNP, APP, MAPT TP53 740/4885FDPS 1231/4885MAPT 3/4885
US-20090023951-A1 Polyalkylated Arylalkyl Sulfonic acids and their salts ALK, CTH, C1S TP53 4525/4885FDPS 1522/4885MAPT 4822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.