Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25507216 | 0.96 | MEN1 (0.36) | MEN1KMT2ACYP2D6KCNH2HRH3 | |
| SCHEMBL25513416 | 0.96 | MEN1 (0.33) | MEN1KMT2ACYP2D6KCNH2HRH3 | |
| SCHEMBL107432 | 0.83 | OPRL1 (0.38) | MEN1KMT2ACYP2D6KCNH2HRH3 | |
| SCHEMBL24185791 | 0.83 | OPRL1 (0.38) | MEN1KMT2ACYP2D6KCNH2HRH3 | |
| SCHEMBL803132 | 0.81 | MEN1 (0.45) | MEN1KMT2ACYP2D6KCNH2HRH3 | |
| SCHEMBL23594004 | 0.81 | MEN1 (0.33) | MEN1KMT2ACYP2D6KCNH2HRH3 | |
| SCHEMBL25659233 | 0.79 | — | — | |
| SCHEMBL25594480 | 0.79 | MEN1 (0.47) | MEN1KMT2ACYP2D6KCNH2HRH3 | |
| SCHEMBL23594121 | 0.78 | CYP2D6 (0.49) | MEN1KMT2ACYP2D6KCNH2HRH3 | |
| SCHEMBL24891108 | 0.78 | HSD11B1 (0.42) | MEN1KMT2ACYP2D6KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4310084-A1 | PYRIDOPYRIMIDINE-BASED COMPOUND AND APPLICATION THEREOF | Jinan University (CN) | 2024-01-24 | — | — | EP | disclosed |
| EP-4180432-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |