Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25668124 | 0.86 | ALDH1A1 (0.34) | CYP1A2CYP2D6ALOX15ALDH1A1GAA | |
| SCHEMBL19766337 | 0.85 | CYP1A2 (0.36) | CYP1A2CYP2D6ALOX15ALDH1A1GAA | |
| SCHEMBL24132476 | 0.82 | CYP1A2 (0.48) | CYP1A2CYP2D6ALOX15ALDH1A1GAA | |
| SCHEMBL9408483 | 0.79 | CYP1A2 (0.41) | CYP1A2CYP2D6ALOX15ALDH1A1GAA | |
| SCHEMBL24589000 | 0.77 | TSHR (0.33) | CYP1A2CYP2D6ALOX15 | |
| SCHEMBL24718649 | 0.77 | TSHR (0.33) | CYP1A2CYP2D6ALOX15 | |
| SCHEMBL22281830 | 0.75 | CYP1A2 (0.44) | CYP1A2CYP2D6ALOX15ALDH1A1GAA | |
| SCHEMBL15369596 | 0.75 | — | — | |
| SCHEMBL18537597 | 0.75 | CYP1A2 (0.44) | CYP1A2CYP2D6ALOX15ALDH1A1GAA | |
| SCHEMBL18624721 | 0.74 | USP2 (0.30) | CYP1A2CYP2D6ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180432-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |