SCHEMBL25480247

SCHEMBL25480247

c1cc(-c2ccc3c4ccccc4c4ccccc4c3c2)cc(-c2cccc3c2c2cccc4c5ccccc5n3c42)c1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
POLB P06746 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
RECQL P46063 1/20 0.33
PLEC Q15149 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
DUSP3 P51452 1/20 0.31
ALK Q9UM73 1/20 0.31
ALKBH5 Q6P6C2 1/20 0.30
FTO Q9C0B1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25487967 0.90 FLT3 (0.33) KDM4EMEN1MAPTKMT2ARECQL
SCHEMBL25459782 0.89 TSPO (0.39) KDM4EMEN1MAPTKMT2APOLB
SCHEMBL25459788 0.89 TSPO (0.39) KDM4EMEN1MAPTKMT2APOLB
SCHEMBL21718312 0.88 KDM4E (0.37) KDM4EMEN1MAPTKMT2APOLB
SCHEMBL23814096 0.88 KDM4E (0.37) KDM4EMEN1MAPTKMT2APOLB
SCHEMBL23814088 0.88 KDM4E (0.37) KDM4EMEN1MAPTKMT2APOLB
SCHEMBL23823568 0.88 TSPO (0.37) KDM4EMEN1MAPTKMT2APOLB
SCHEMBL23814191 0.88 TSPO (0.37) KDM4EMEN1MAPTKMT2APOLB
SCHEMBL21473026 0.85 TSPO (0.30)
SCHEMBL23823661 0.85 KDM4E (0.39) KDM4EMEN1MAPTKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 KDM4E 2090/4885MEN1 1251/4885MAPT 507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.