Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TERT | O14746 | 3/20 | 0.32 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26327371 | 0.85 | SLC2A1 (0.31) | SLC2A1EHMT2L3MBTL1ALDH1A1MAPT | |
| SCHEMBL23999409 | 0.83 | LRRK2 (0.40) | SLC2A1EHMT2L3MBTL1TERTDOT1L | |
| SCHEMBL30180298 | 0.83 | KDR (0.39) | KDR | |
| SCHEMBL23999444 | 0.83 | KDR (0.39) | KDR | |
| SCHEMBL23999480 | 0.81 | DNMT1 (0.38) | MAPTPOLBSMN1; SMN2MAPK1RAD52 | |
| SCHEMBL23999592 | 0.80 | KDR (0.39) | KDR | |
| SCHEMBL30180366 | 0.80 | MAPT (0.46) | SLC2A1MAPTPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL23999377 | 0.80 | MAPT (0.46) | SLC2A1MAPTPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL25495797 | 0.78 | KDR (0.37) | KDR | |
| SCHEMBL23999399 | 0.76 | MAPKAPK2 (0.42) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |