Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 5/20 | 0.42 |
| ▸ | GSK3B | P49841 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 11/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.41 |
| ▸ | GAA | P10253 | 9/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37707 | 0.72 | GSK3A (0.48) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL9310226 | 0.72 | VDR (0.52) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL8388898 | 0.71 | GSK3A (0.40) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL16098883 | 0.71 | GSK3A (0.47) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL3027543 | 0.68 | GSK3A (0.44) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL25573 | 0.67 | GSK3A (0.47) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL1194880 | 0.67 | GSK3A (0.47) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL12333650 | 0.67 | GSK3A (0.47) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL2148466 | 0.66 | MAPT (0.44) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL8580463 | 0.66 | KMT2A (0.46) | GSK3AGSK3BMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11618825-B2 | Rhodamine dyes and conjugates | PHARMACOPHOTONICS, INC. (US) | 2023-04-04 | — | — | US | disclosed |
| US-20210403719-A1 | RHODAMINE DYES AND CONJUGATES | PHARMACOPHOTONICS INC D/B/A FAST DIAGNOSTICS (US) | 2021-12-30 | — | — | US | disclosed |
| US-11130865-B2 | Rhodamine dyes and conjugates | PHARMACOPHOTONICS, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-20200109289-A1 | NOVEL RHODAMINE DYES AND CONJUGATES | PHARMACOPHOTONICS, INC. D/B/A FAST BIOMEDICAL (US) | 2020-04-09 | — | — | US | disclosed |
| CN-109456341-A | Sulfonamide rhodamine compounds with alkynyl or azido derivative sites, and preparation method and application thereof | 大连理工大学 | 2019-03-12 | — | — | CN | disclosed |
| US-20190016896-A1 | NOVEL RHODAMINE DYES AND CONJUGATES | PHARMACOPHOTONICS, INC. D/B/A FAST DIAGNOSTICS | 2019-01-17 | — | — | US | disclosed |
| US-9938410-B2 | Rhodamine dyes and conjugates | PHARMACOPHOTONICS, INC. (US) | 2018-04-10 | — | — | US | disclosed |
| US-20160208101-A1 | NOVEL RHODAMINE DYES AND CONJUGATES | PHARMACOPHOTONICS, INC. D/B/A FAST DIAGNOSTICS | 2016-07-21 | — | — | US | disclosed |
| US-9169398-B2 | Rhodamine dyes and conjugates | PHARMACOPHOTONICS, INC. (US) | 2015-10-27 | — | — | US | disclosed |
| US-20140256946-A1 | NOVEL RHODAMINE DYES AND CONJUGATES | PHARMACOPHOTONICS, INC. D/B/A FAST DIAGNOSTICS (US) | 2014-09-11 | — | — | US | disclosed |
| US-8809531-B2 | Rhodamine dyes and conjugates | PHARMACOPHOTONICS, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20130096309-A1 | NOVEL RHODAMINE DYES AND CONJUGATES | PHARMACOPHOTONICS, INC. D/B/A FAST DIAGNOSTICS | 2013-04-18 | — | — | US | disclosed |
| EP-2552492-A2 | SINGLE ISOMERIC CONJUGATES OF RHODAMINE DYES | Pharmacophotonics, Inc. (US) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011123820-A2 | NOVEL RHODAMINE DYES AND CONJUGATES | PHARMACOPHOTONICS, INC. (US) | 2011-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403719-A1 | RHODAMINE DYES AND CONJUGATES | RCN1, RDX, CIT | GSK3A 4784/4885GSK3B 4753/4885MEN1 1824/4885 |
| US-20190016896-A1 | NOVEL RHODAMINE DYES AND CONJUGATES | RDX, CIT, RCN1 | GSK3A 4767/4885GSK3B 4727/4885MEN1 2307/4885 |
| US-11618825-B2 | Rhodamine dyes and conjugates | RCN1, RDX, CIT | GSK3A 4784/4885GSK3B 4753/4885MEN1 1824/4885 |
| US-11130865-B2 | Rhodamine dyes and conjugates | RCN1, RDX, CIT | GSK3A 4784/4885GSK3B 4753/4885MEN1 1824/4885 |
| US-20200109289-A1 | NOVEL RHODAMINE DYES AND CONJUGATES | RDX, CIT, RCN1 | GSK3A 4767/4885GSK3B 4727/4885MEN1 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.