SCHEMBL25486189

SCHEMBL25486189

Cc1ccc2c(c1)C(C)(C)C(/C=C/C1=C(Cl)/C(=C/C=C3/N(CCCCCOC=O)c4ccc(S(=O)(=O)O)cc4C3(C)C)CCC1)=[N+]2CCCCCOC=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.44
FOLH1 Q04609 4/20 0.44
HTR1A P08908 1/20 0.43
PRMT1 Q99873 3/20 0.40
PRMT5 O14744 1/20 0.39
CARM1 Q86X55 1/20 0.39
PRMT8 Q9NR22 1/20 0.39
FOLR1 P15328 5/20 0.39
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
DPP8 Q6V1X1 1/20 0.36
DPP9 Q86TI2 1/20 0.36
TLR8 Q9NR97 1/20 0.36
OPRM1 P35372 1/20 0.36
OPRK1 P41145 1/20 0.36
ADORA1 P30542 1/20 0.35
HRH2 P25021 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25486206 0.91 FOLH1 (0.52) PTPN1FOLH1HTR1APRMT1PRMT5
SCHEMBL17694083 0.91 PTPN1 (0.54) PTPN1FOLH1HTR1APRMT1PRMT5
SCHEMBL14703589 0.90 PTPN1 (0.49) PTPN1FOLH1HTR1APRMT1PRMT5
SCHEMBL17268217 0.89 PTPN1 (0.44) PTPN1FOLH1HTR1APRMT1PRMT5
SCHEMBL20045202 0.88 PTPN1 (0.51) PTPN1FOLH1HTR1APRMT1PRMT5
SCHEMBL26207804 0.87 FOLH1 (0.41) PTPN1FOLH1HTR1APRMT1PRMT5
SCHEMBL18263260 0.87 PTPN1 (0.57) PTPN1FOLH1HTR1APRMT1PRMT5
SCHEMBL15095695 0.87 PTPN1 (0.57) PTPN1FOLH1HTR1APRMT1PRMT5
SCHEMBL18263258 0.87 PTPN1 (0.57) PTPN1FOLH1HTR1APRMT1PRMT5
SCHEMBL25489625 0.87 FOLH1 (0.50) PTPN1FOLH1HTR1APRMT1PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159547-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159547-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME CD209, MRPL9, RXFP1 PTPN1 1701/4885FOLH1 1632/4885HTR1A 554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.