Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | FOLR1 | P15328 | 6/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26207782 | 0.94 | FOLH1 (0.44) | FOLH1HTR1APTPN1PRMT1PRMT5 | |
| SCHEMBL859682 | 0.90 | PRMT1 (0.43) | FOLH1HTR1APTPN1PRMT1PRMT5 | |
| SCHEMBL31353033 | 0.89 | FOLH1 (0.45) | FOLH1HTR1APTPN1PRMT1PRMT5 | |
| SCHEMBL17268217 | 0.88 | PTPN1 (0.44) | FOLH1HTR1APTPN1PRMT1PRMT5 | |
| SCHEMBL17694083 | 0.88 | PTPN1 (0.54) | FOLH1HTR1APTPN1PRMT1PRMT5 | |
| SCHEMBL25486189 | 0.87 | PTPN1 (0.44) | FOLH1HTR1APTPN1PRMT1PRMT5 | |
| SCHEMBL14272549 | 0.87 | PRMT1 (0.50) | FOLH1HTR1APTPN1PRMT1PRMT5 | |
| SCHEMBL13222312 | 0.87 | PRMT1 (0.50) | FOLH1HTR1APTPN1PRMT1PRMT5 | |
| SCHEMBL20381943 | 0.86 | PRMT1 (0.47) | FOLH1HTR1APTPN1PRMT1PRMT5 | |
| SCHEMBL20045202 | 0.86 | PTPN1 (0.51) | FOLH1HTR1APTPN1PRMT1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746086-B2 | Non-aggregating heptamethine cyanine fluorophores for in vivo imaging | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746086-B2 | Non-aggregating heptamethine cyanine fluorophores for in vivo imaging | CNDP2, MSN, CHAT | FOLH1 420/4885HTR1A 102/4885PTPN1 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.